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FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation
Cell fate decision upon prolonged mitotic arrest induced by microtubule-targeting agents depends on the activity of the tumor suppressor and F-box protein FBXW7. FBXW7 promotes mitotic cell death and prevents premature escape from mitosis through mitotic slippage. Mitotic slippage is a process that...
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| Publicado en: | Cell Death Differ |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206008/ https://ncbi.nlm.nih.gov/pubmed/31285543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0385-7 |
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