Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation

Exosomes from human umbilical cord mesenchymal stem cells (hucMSC-Ex) have been suggested as novel nanomaterials for regenerative medicine. Here we explored the roles of hucMSC-Ex through regulating Yes-associated protein (YAP) in renal injury repair by using rat unilateral ureteral obstruction (UUO...

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Publicat a:Cell Death Dis
Autors principals: Ji, Cheng, Zhang, Jiahui, Zhu, Yuan, Shi, Hui, Yin, Siqi, Sun, Fengtian, Wang, Qiongni, Zhang, Leilei, Yan, Yongmin, Zhang, Xu, Xu, Wenrong, Qian, Hui
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205986/
https://ncbi.nlm.nih.gov/pubmed/32382019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2510-4
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