Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy

Abstract Background The administration of cisplatin is limited due to its nephrotoxic side effects, and prevention of this nephrotoxicity of cisplatin is difficult. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic approach for tissue injury. In this study, we...

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Detalhes bibliográficos
Main Authors: Bingying Wang, Haoyuan Jia, Bin Zhang, Juanjuan Wang, Cheng Ji, Xueming Zhu, Yongmin Yan, Lei Yin, Jing Yu, Hui Qian, Wenrong Xu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-04-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Human umbilical cord mesenchymal stem cell
Exosome
Cisplatin
Nephrotoxicity
Autophagy
Acesso em linha:http://link.springer.com/article/10.1186/s13287-016-0463-4
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