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Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma
Somatic oncogenic mutation of BRAF coupled with inactivation of PTEN constitute a frequent combination of genomic alterations driving the development of human melanoma. Mice genetically engineered to conditionally express oncogenic Braf(V600E) and inactivate Pten in melanocytes following tamoxifen t...
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| Publicat a: | Cell Death Differ |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205870/ https://ncbi.nlm.nih.gov/pubmed/31065107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0333-6 |
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