Chromatin remodellers Brg1 and Bptf are required for normal gene expression and progression of oncogenic Braf-driven mouse melanoma

Somatic oncogenic mutation of BRAF coupled with inactivation of PTEN constitute a frequent combination of genomic alterations driving the development of human melanoma. Mice genetically engineered to conditionally express oncogenic Braf(V600E) and inactivate Pten in melanocytes following tamoxifen t...

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Udgivet i:Cell Death Differ
Main Authors: Laurette, Patrick, Coassolo, Sébastien, Davidson, Guillaume, Michel, Isabelle, Gambi, Giovanni, Yao, Wenjin, Sohier, Pierre, Li, Mei, Mengus, Gabrielle, Larue, Lionel, Davidson, Irwin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205870/
https://ncbi.nlm.nih.gov/pubmed/31065107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0333-6
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