Enhanced thioredoxin, glutathione and Nrf2 antioxidant systems by safflower extract and aceglutamide attenuate cerebral ischaemia/reperfusion injury

A large number of reactive oxygen species (ROS) aggravate cerebral damage after ischaemia/reperfusion (I/R). Glutathione (GSH), thioredoxin (Trx) and nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) represent three major antioxidant systems and play vital roles in affecting each other in eliminati...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Jingjing, Zhou, Rui, Xiang, Changpei, Fan, Fangfang, Gao, Jinhuan, Zhang, Yi, Tang, Shihuan, Xu, Haiyu, Yang, Hongjun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205826/
https://ncbi.nlm.nih.gov/pubmed/32266795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15099
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