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FGF21 induces autophagy‐mediated cholesterol efflux to inhibit atherogenesis via RACK1 up‐regulation

Fibroblast growth factor 21 (FGF21) acts as an anti‐atherosclerotic agent. However, the specific mechanisms governing this regulatory activity are unclear. Autophagy is a highly conserved cell stress response which regulates atherosclerosis (AS) by reducing lipid droplet degradation in foam cells. W...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Xiaolong, Lin, Dongmin, Guo, Liu, Mihua, Zuo, Wang, Huijun, Hu, Qiufen, Tan, XueMei, Hu, Wensheng, Lin, Yuping, Pan, Jun, Lin, Zhaolin, Zeng
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205825/
https://ncbi.nlm.nih.gov/pubmed/32227589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15118
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