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Convex Combination Sequence Kernel Association Test for Rare Variant Studies
We propose a novel variant set test for rare-variant association studies that leverages multiple SNV annotations. Our approach optimizes a convex combination of different Sequence Kernel Association Test (SKAT) statistics, where each statistic is constructed from a different annotation and combinati...
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| Publicado no: | Genet Epidemiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205561/ https://ncbi.nlm.nih.gov/pubmed/32100372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22287 |
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