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Loss of Glp2r signaling activates hepatic stellate cells and exacerbates diet-induced steatohepatitis in mice
A glucagon-like peptide-2 (GLP-2) analog is used in individuals with intestinal failure who are at risk for liver disease, yet the hepatic actions of GLP-2 are not understood. Treatment of high-fat diet–fed (HFD-fed) mice with GLP-2 did not modify the development of hepatosteatosis or hepatic inflam...
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| Pubblicato in: | JCI Insight |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205439/ https://ncbi.nlm.nih.gov/pubmed/32191643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136907 |
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