The C5a/C5aR2 axis promotes renal inflammation and tissue damage

C5a is a potent inflammatory mediator that binds C5aR1 and C5aR2. Although pathogenic roles of the C5a/C5aR1 axis in inflammatory disorders are well documented, the roles for the C5a/C5aR2 axis in inflammatory disorders and underlying mechanisms remain unclear. Here, we show that the C5a/C5aR2 axis...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Zhang, Ting, Wu, Kun-yi, Ma, Ning, Wei, Ling-lin, Garstka, Malgorzata, Zhou, Wuding, Li, Ke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205289/
https://ncbi.nlm.nih.gov/pubmed/32191644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134081
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