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The Controversial C5a Receptor C5aR2: Its Role in Health and Disease

After the discovery of the C5a receptor C5aR1, C5aR2 is the second receptor found to bind C5a and its des-arginine form. As a heptahelical G protein-coupled receptor but devoid of the intracellular Gα signal, C5aR2 is special and confusing. Ramifications and controversies about C5aR2 are under debat...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Zhang, Ting, Garstka, Malgorzata A., Li, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494583/
https://ncbi.nlm.nih.gov/pubmed/28706957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8193932
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