Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression

Renal cysts are the defining feature of autosomal dominant polycystic kidney disease (ADPKD); however, the substantial interstitial inflammation is an often-overlooked aspect of this disorder. Recent studies suggest that immune cells in the cyst microenvironment affect ADPKD progression. Here we rep...

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Pubblicato in:JCI Insight
Autori principali: Lakhia, Ronak, Yheskel, Matanel, Flaten, Andrea, Ramalingam, Harini, Aboudehen, Karam, Ferrè, Silvia, Biggers, Laurence, Mishra, Abheepsa, Chaney, Christopher, Wallace, Darren P., Carroll, Thomas, Igarashi, Peter, Patel, Vishal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205276/
https://ncbi.nlm.nih.gov/pubmed/32182218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133785
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