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Design, Synthesis, and Evaluation of Novel Anti-Trypanosomal Compounds

Human African trypanosomiasis (HAT) is a deadly neglected tropical disease caused by the protozoan parasite Trypanosoma brucei. During the course of screening a collection of diverse nitrogenous heterocycles, we discovered two novel compounds that contain the tetracyclic core of the Yohimbine and Co...

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Vydáno v:Tetrahedron
Hlavní autoři: Lepovitz, Lance T., Meis, Alan R., Thomas, Sarah M., Wiedeman, Justin, Pham, Alexandra, Mensa-Wilmot, Kojo, Martin, Stephen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204524/
https://ncbi.nlm.nih.gov/pubmed/32382196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2020.131086
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