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Baseline-adjusted proportional odds models for the quantification of treatment effects in trials with ordinal sum score outcomes

BACKGROUND: Sum scores of ordinal outcomes are common in randomized clinical trials. The approaches routinely employed for assessing treatment effects, such as t-tests or Wilcoxon tests, are not particularly powerful in detecting changes in relevant parameters or lack the ability to incorporate base...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Buri, Muriel, Curt, Armin, Steeves, John, Hothorn, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204322/
https://ncbi.nlm.nih.gov/pubmed/32375705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-00984-2
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