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Phosphorylation-Dependent Pin1 Isomerization of ATR: Its Role in Regulating ATR’s Anti-apoptotic Function at Mitochondria, and the Implications in Cancer

Peptidyl-prolyl isomerization is an important post-translational modification of protein because proline is the only amino acid that can stably exist as cis and trans, while other amino acids are in the trans conformation in protein backbones. This makes prolyl isomerization a unique mechanism for c...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Makinwa, Yetunde, Musich, Phillip R., Zou, Yue
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203486/
https://ncbi.nlm.nih.gov/pubmed/32426354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00281
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