Exploring the Potential of CRISPR-Cas9 Under Challenging Conditions: Facing High-Copy Plasmids and Counteracting Beta-Lactam Resistance in Clinical Strains of Enterobacteriaceae

The antimicrobial resistance (AMR) crisis urgently requires countermeasures for reducing the dissemination of plasmid-borne resistance genes. Of particular concern are opportunistic pathogens of Enterobacteriaceae. One innovative approach is the CRISPR-Cas9 system which has recently been used for pl...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Tagliaferri, Thaysa Leite, Guimarães, Natália Rocha, Pereira, Marcella de Paula Martins, Vilela, Liza Figueiredo Felicori, Horz, Hans-Peter, dos Santos, Simone Gonçalves, Mendes, Tiago Antônio de Oliveira
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203346/
https://ncbi.nlm.nih.gov/pubmed/32425894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00578
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