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Chromatin and Cytoskeletal Tethering Determine Nuclear Morphology in Progerin-Expressing Cells

The nuclear morphology of eukaryotic cells is determined by the interplay between the lamina forming the nuclear skeleton, the chromatin inside the nucleus, and the coupling with the cytoskeleton. Nuclear alterations are often associated with pathological conditions as in Hutchinson-Gilford progeria...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Lionetti, Maria Chiara, Bonfanti, Silvia, Fumagalli, Maria Rita, Budrikis, Zoe, Font-Clos, Francesc, Costantini, Giulio, Chepizhko, Oleksandr, Zapperi, Stefano, La Porta, Caterina A.M.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203074/
https://ncbi.nlm.nih.gov/pubmed/32320674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.04.001
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