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Protein accumulation in the endoplasmic reticulum as a non-equilibrium phase transition
Several neurological disorders are associated with the aggregation of aberrant proteins, often localized in intracellular organelles such as the endoplasmic reticulum. Here we study protein aggregation kinetics by mean-field reactions and three dimensional Monte carlo simulations of diffusion-limite...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048836/ https://ncbi.nlm.nih.gov/pubmed/24722051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4620 |
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