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Checkpoint inhibition and CAR T cells for the Treatment of Glioblastoma

INTRODUCTION: Glioblastoma (GBM) is a highly aggressive brain tumor and is one of the most lethal human cancers. Chimeric antigen receptor (CAR) T cell therapy has markedly improved survival in previously incurable disease; however, this vanguard treatment still faces challenges in GBM. Likewise, ch...

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Bibliographische Detailangaben
Veröffentlicht in:Expert Opin Biol Ther
Hauptverfasser: Shen, Steven H., Woroniecka, Karolina, Barbour, Andrew B., Fecci, Peter E., Sanchez-Perez, Luis, Sampson, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202971/
https://ncbi.nlm.nih.gov/pubmed/32027536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2020.1727436
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