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Prospects of immune checkpoint modulators in the treatment of glioblastoma

Glioblastoma is the most common primary brain tumour in adults. Prognosis is poor: even with the current gold-standard first-line treatment—maximal safe resection and combination of radiotherapy with temozolomide chemotherapy—the median overall survival time is only approximately 15–17 months, becau...

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Detalhes bibliográficos
Publicado no:Nat Rev Neurol
Main Authors: Preusser, Matthias, Lim, Michael, Hafler, David A., Reardon, David A., Sampson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782584/
https://ncbi.nlm.nih.gov/pubmed/26260659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2015.139
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