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Ensembles of Breathing Nucleosomes: A Computational Study

About three-fourths of the human DNA molecules are wrapped into nucleosomes, protein spools with DNA. Nucleosomes are highly dynamic, transiently exposing their DNA through spontaneous unspooling. Recent experiments allowed to observe the DNA of an ensemble of such breathing nucleosomes through x-ra...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: van Deelen, Koen, Schiessel, Helmut, de Bruin, Lennart
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202939/
https://ncbi.nlm.nih.gov/pubmed/31882248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.3395
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