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Ensembles of Breathing Nucleosomes: A Computational Study

About three-fourths of the human DNA molecules are wrapped into nucleosomes, protein spools with DNA. Nucleosomes are highly dynamic, transiently exposing their DNA through spontaneous unspooling. Recent experiments allowed to observe the DNA of an ensemble of such breathing nucleosomes through x-ra...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: van Deelen, Koen, Schiessel, Helmut, de Bruin, Lennart
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202939/
https://ncbi.nlm.nih.gov/pubmed/31882248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.3395
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