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Valid post-clustering differential analysis for single-cell RNA-Seq

Single-cell computational pipelines involve two critical steps: organizing cells (clustering) and identifying the markers driving this organization (differential expression analysis). State-of-the-art pipelines perform differential analysis after clustering on the same dataset. We observe that becau...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Syst
Main Authors: Zhang, Jesse M., Kamath, Govinda M., Tse, David N.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202736/
https://ncbi.nlm.nih.gov/pubmed/31521605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2019.07.012
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