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Inferring Spatial Organization of Individual Topologically Associated Domains via Piecewise Helical Model

The recently developed Hi-C technology enables a genome-wide view of chromosome spatial organizations, and has shed deep insights into genome structure and genome function. However, multiple sources of uncertainties make downstream data analysis and interpretation challenging. Specifically, statisti...

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Dettagli Bibliografici
Pubblicato in:IEEE/ACM Trans Comput Biol Bioinform
Autori principali: Rongrong, Zhang, Hu, Ming, Zhu, Yu, Qin, Zhaohui, Deng, Ke, Liu, Jun S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202374/
https://ncbi.nlm.nih.gov/pubmed/30113897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2018.2865349
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