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Inferring Spatial Organization of Individual Topologically Associated Domains via Piecewise Helical Model

The recently developed Hi-C technology enables a genome-wide view of chromosome spatial organizations, and has shed deep insights into genome structure and genome function. However, multiple sources of uncertainties make downstream data analysis and interpretation challenging. Specifically, statisti...

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Detalhes bibliográficos
Publicado no:IEEE/ACM Trans Comput Biol Bioinform
Main Authors: Rongrong, Zhang, Hu, Ming, Zhu, Yu, Qin, Zhaohui, Deng, Ke, Liu, Jun S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202374/
https://ncbi.nlm.nih.gov/pubmed/30113897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TCBB.2018.2865349
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