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A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate

BACKGROUND: A broad range of aromatic compounds can be degraded by enteric bacteria, and hydroxyphenylacetic acid (HPA) degrading bacteria are the most widespread. Majority of Escherichia coli strains can use both the structural isomers of HPA, 3HPA and 4HPA, as the sole carbon source, which are cat...

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Publicado en:BMC Microbiol
Main Authors: Kim, Hanseol, Kim, Sinyeon, Kim, Dohyeon, Yoon, Sung Ho
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201708/
https://ncbi.nlm.nih.gov/pubmed/32375644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-020-01798-4
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