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A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate

BACKGROUND: A broad range of aromatic compounds can be degraded by enteric bacteria, and hydroxyphenylacetic acid (HPA) degrading bacteria are the most widespread. Majority of Escherichia coli strains can use both the structural isomers of HPA, 3HPA and 4HPA, as the sole carbon source, which are cat...

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Veröffentlicht in:BMC Microbiol
Hauptverfasser: Kim, Hanseol, Kim, Sinyeon, Kim, Dohyeon, Yoon, Sung Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201708/
https://ncbi.nlm.nih.gov/pubmed/32375644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-020-01798-4
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