A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate

BACKGROUND: A broad range of aromatic compounds can be degraded by enteric bacteria, and hydroxyphenylacetic acid (HPA) degrading bacteria are the most widespread. Majority of Escherichia coli strains can use both the structural isomers of HPA, 3HPA and 4HPA, as the sole carbon source, which are cat...

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Udgivet i:BMC Microbiol
Main Authors: Kim, Hanseol, Kim, Sinyeon, Kim, Dohyeon, Yoon, Sung Ho
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201708/
https://ncbi.nlm.nih.gov/pubmed/32375644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-020-01798-4
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