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Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays

Mutations in the only known iron exporter ferroportin (FPN) in humans are associated with the autosomal dominantly inherited iron overload disorder ferroportin disease or type IV hereditary hemochromatosis (HH). While our knowledge of the central role of FPN in iron homeostasis has grown in the last...

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Udgivet i:Biosci Rep
Main Authors: Rishi, Gautam, Secondes, Eriza S., Wallace, Daniel F., Subramaniam, V. Nathan
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201565/
https://ncbi.nlm.nih.gov/pubmed/32301493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20191499
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