Dysregulated hepcidin response to dietary iron in male mice with reduced Gnpat expression

Exome sequencing has identified the glyceronephosphate O-acyltransferase (GNPAT) gene as a genetic modifier of iron overload in hereditary hemochromatosis (HH). Subjects with HFE (Homeostatic Iron Regulator) p.C282Y mutations and the GNPAT p.D519G variant had more iron loading compared with subjects...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Rishi, Gautam, Secondes, Eriza S., Asplett, Kiran, Wallace, Daniel F., Ostini, Lesa, Berger, Johannes, Subramaniam, V. Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Gastrointestinal, Renal & Hepatic Systems
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441371/
https://ncbi.nlm.nih.gov/pubmed/32766721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201508
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados