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CTLA4-Ig Abatacept Ameliorates Proteinuria by Regulating Circulating Treg/IL-17 in Adriamycin-Induced Nephropathy Rats

OBJECTIVE: This study is aimed at investigating the efficacy of CTLA4-Ig abatacept in normalizing proteinuria and its possible mechanism in adriamycin-induced nephropathy (AIN) rats. METHODS: A total of 32 healthy male Sprague-Dawley rats were randomly divided into a normal group, an AIN group, an a...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Shuai, Lanjun, Cheng, Qia, Shen, Tian, Yi, Zhuwen, Wu, Xiaochuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201454/
https://ncbi.nlm.nih.gov/pubmed/32420329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2347827
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