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Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced-nephropathy rats

The aim of this study was to investigate the effects of simvastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, on inflammation and glomerulosclerosis in Adriamycin (ADR)-induced nephropathy. Male Sprague-Dawley rats were randomly divided into control, ADR...

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Detalhes bibliográficos
Publicado no:Pediatr Nephrol
Main Authors: Zhang, Wei, Li, Qiu, Wang, Lijia, Yang, Xiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811526/
https://ncbi.nlm.nih.gov/pubmed/18791746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-008-0933-8
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