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Computational Modeling of Human Mesenchymal Stromal Cell Proliferation and Extra-Cellular Matrix Production in 3D Porous Scaffolds in a Perfusion Bioreactor: The Effect of Growth Factors

Stem cell expansion on 3D porous scaffolds cultured in bioreactor systems has been shown to be beneficial for maintenance of the original cell functionality in tissue engineering strategies (TE). However, the production of extracellular matrix (ECM) makes harvesting the progenitor cell population fr...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Mehrian, Mohammad, Lambrechts, Toon, Papantoniou, Ioannis, Geris, Liesbet
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201129/
https://ncbi.nlm.nih.gov/pubmed/32411692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00376
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