Immersed Boundary Models for Quantifying Flow-Induced Mechanical Stimuli on Stem Cells Seeded on 3D Scaffolds in Perfusion Bioreactors

Perfusion bioreactors regulate flow conditions in order to provide cells with oxygen, nutrients and flow-associated mechanical stimuli. Locally, these flow conditions can vary depending on the scaffold geometry, cellular confluency and amount of extra cellular matrix deposition. In this study, a nov...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Guyot, Yann, Smeets, Bart, Odenthal, Tim, Subramani, Ramesh, Luyten, Frank P., Ramon, Herman, Papantoniou, Ioannis, Geris, Liesbet
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033382/
https://ncbi.nlm.nih.gov/pubmed/27658116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005108
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