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3′-UTR Shortening Contributes to Subtype-Specific Cancer Growth by Breaking Stable ceRNA Crosstalk of Housekeeping Genes

Shortening of 3′UTRs (3′US) through alternative polyadenylation is a post-transcriptional mechanism that regulates the expression of hundreds of genes in human cancers. In breast cancer, different subtypes of tumor samples, such as estrogen receptor positive and negative (ER+ and ER–), are character...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Fan, Zhenjiang, Kim, Soyeon, Bai, Yulong, Diergaarde, Brenda, Park, Hyun Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201092/
https://ncbi.nlm.nih.gov/pubmed/32411683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00334
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