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Complexities of post-transcriptional regulation and the modeling of ceRNA crosstalk

Control of gene and protein expression is required for cellular homeostasis and is disrupted in disease. Following transcription, mRNA turnover and translation is modulated, most notably by microRNAs (miRNAs). This modulation is controlled by transcriptional and post-transcriptional events that alte...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Smillie, Claire L., Sirey, Tamara, Ponting, Chris P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935048/
https://ncbi.nlm.nih.gov/pubmed/29569941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2018.1447542
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