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Pseudogenes regulate parental gene expression via ceRNA network
The concept of competitive endogenous RNA (ceRNA) was first proposed by Salmena and colleagues. Evidence suggests that pseudogene RNAs can act as a ‘sponge’ through competitive binding of common miRNA, releasing or attenuating repression through sequestering miRNAs away from parental mRNA. In theory...
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| Veröffentlicht in: | J Cell Mol Med |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5192809/ https://ncbi.nlm.nih.gov/pubmed/27561207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12952 |
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