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Eliminating primer dimers and improving SNP detection using self-avoiding molecular recognition systems

Despite its widespread value to molecular biology, the polymerase chain reaction (PCR) encounters modes that unproductively consume PCR resources and prevent clean signals, especially when high sensitivity, high SNP discrimination, and high multiplexing are sought. Here, we show how “self-avoiding m...

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Detalhes bibliográficos
Publicado no:Biol Methods Protoc
Main Authors: Yang, Zunyi, Le, Jennifer T, Hutter, Daniel, Bradley, Kevin M, Overton, Benjamin R, McLendon, Chris, Benner, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200914/
https://ncbi.nlm.nih.gov/pubmed/32395633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpaa004
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