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Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system

The CRISPR/Cas system has recently emerged as a powerful tool to engineer the genome of an organism. The system is adopted from bacteria where it confers immunity against invading foreign DNA. This work reports the first successful use of the CRISPR/Cas system in Caenorhabditis briggsae (a cousin of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Methods Protoc
Hauptverfasser: Culp, Elizabeth, Richman, Cory, Sharanya, Devika, Jhaveri, Nikita, van den Berg, Wouter, Gupta, Bhagwati P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200835/
https://ncbi.nlm.nih.gov/pubmed/32395632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpaa003
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