Genome editing in the nematode Caenorhabditis briggsae using the CRISPR/Cas9 system

The CRISPR/Cas system has recently emerged as a powerful tool to engineer the genome of an organism. The system is adopted from bacteria where it confers immunity against invading foreign DNA. This work reports the first successful use of the CRISPR/Cas system in Caenorhabditis briggsae (a cousin of...

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Bibliographic Details
Published in:Biol Methods Protoc
Main Authors: Culp, Elizabeth, Richman, Cory, Sharanya, Devika, Jhaveri, Nikita, van den Berg, Wouter, Gupta, Bhagwati P
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Methods Manuscript
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200835/
https://ncbi.nlm.nih.gov/pubmed/32395632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpaa003
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