Enhanced Cerebral Blood Volume under Normobaric Hyperoxia in the J20-hAPP Mouse Model of Alzheimer’s Disease

Early impairments to neurovascular coupling have been proposed to be a key pathogenic factor in the onset and progression of Alzheimer’s disease (AD). Studies have shown impaired neurovascular function in several mouse models of AD, including the J20-hAPP mouse. In this study, we aimed to investigat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shabir, Osman, Sharp, Paul, Rebollar, Monica A., Boorman, Luke, Howarth, Clare, Wharton, Stephen B., Francis, Sheila E., Berwick, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200762/
https://ncbi.nlm.nih.gov/pubmed/32371859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64334-4
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