The mechanism of loop C-neonicotinoid interactions at insect nicotinic acetylcholine receptor α1 subunit predicts resistance emergence in pests

Neonicotinoids selectively modulate insect nicotinic acetylcholine receptors (insect nAChRs). Studies have shown that serine with ability to form a hydrogen bond in loop C of some insect nAChR α subunits and glutamate with a negative charge at the corresponding position in vertebrate nAChRs may cont...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shimada, Shota, Kamiya, Masaki, Shigetou, Sho, Tomiyama, Kakeru, Komori, Yuma, Magara, Leo, Ihara, Makoto, Matsuda, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200709/
https://ncbi.nlm.nih.gov/pubmed/32371996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64258-z
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