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Differential effects of ‘resurrecting' Csp pseudoproteases during Clostridioides difficile spore germination

Clostridioides difficile is a spore-forming bacterial pathogen that is the leading cause of hospital-acquired gastroenteritis. C. difficile infections begin when its spore form germinates in the gut upon sensing bile acids. These germinants induce a proteolytic signaling cascade controlled by three...

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Vydáno v:Biochem J
Hlavní autoři: Donnelly, M. Lauren, Forster, Emily R., Rohlfing, Amy E., Shen, Aimee
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200643/
https://ncbi.nlm.nih.gov/pubmed/32242623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190875
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