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The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals

The gastrointestinal pathogen, Clostridioides difficile, initiates infection when its metabolically dormant spore form germinates in the mammalian gut. While most spore-forming bacteria use transmembrane germinant receptors to sense nutrient germinants, C. difficile is thought to use the soluble pse...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Rohlfing, Amy E., Eckenroth, Brian E., Forster, Emily R., Kevorkian, Yuzo, Donnelly, M. Lauren, Benito de la Puebla, Hector, Doublié, Sylvie, Shen, Aimee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636752/
https://ncbi.nlm.nih.gov/pubmed/31276487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008224
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