Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury

Tissue fibrosis is a hallmark of overuse musculoskeletal injuries and contributes to functional declines. We tested whether inhibition of CCN2 (cellular communication network factor 2, previously known as connective tissue growth factor, CTGF) using a specific antibody (termed FG‐3019 or pamrevlumab...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Barbe, Mary F., Hilliard, Brendan A., Amin, Mamta, Harris, Michele Y., Hobson, Lucas J., Cruz, Geneva E., Popoff, Steven N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200299/
https://ncbi.nlm.nih.gov/pubmed/32227398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000240RR
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