Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells.

Emerging evidence of crosstalk between glomerular cells in pathological settings provide opportunities for novel therapeutic discovery. Here we investigated underlying mechanisms of early events leading to filtration barrier defects of podocyte and glomerular endothelial cell crosstalk in the mouse...

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Udgivet i:Kidney Int
Main Authors: Ebefors, Kerstin, Wiener, Robert J., Yu, Liping, Azeloglu, Evren U., Yi, Zhengzi, Jia, Fu, Zhang, Weijia, Baron, Margaret H., He, John C., Haraldsson, Börje, Daehn, Ilse
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7200072/
https://ncbi.nlm.nih.gov/pubmed/31402170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.05.007
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