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Activation of c-Jun by human cytomegalovirus UL42 through JNK activation

c-Jun is a major component of the AP-1 transactivator complex. In this report, we demonstrated that AP-1 was activated by the expression of UL42, a human cytomegalovirus-encoded membrane protein that has two PPXY (PY) motifs and a C-terminal transmembrane domain (TMD). Although UL42 interacts with I...

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Pubblicato in:PLoS One
Autori principali: Koshizuka, Tetsuo, Inoue, Naoki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199950/
https://ncbi.nlm.nih.gov/pubmed/32369499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232635
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