Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa

One of the most successful HIV vaccines to date, the RV144 vaccine tested in Thailand demonstratedcorrelates of protection including cross-clade V1V2 IgG breadth, Env-specific CD4+ T cell polyfunctionality, and antibody-dependent cellular cytotoxicity (ADCC) in vaccinees with low IgA binding. The HI...

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Détails bibliographiques
Publié dans:Sci Transl Med
Auteurs principaux: Gray, Glenda E., Huang, Ying, Grunenberg, Nicole, Laher, Fatima, Roux, Surita, Andersen-Nissen, Erica, De Rosa, Stephen C., Flach, Britta, Randhawa, April K., Jensen, Ryan, Swann, Edith M., Bekker, Linda-Gail, Innes, Craig, Lazarus, Erica, Morris, Lynn, Mkhize, Nonhlanhla N., Ferrari, Guido, Montefiori, David C., Shen, Xiaoying, Sawant, Sheetal, Yates, Nicole, Hural, John, Isaacs, Abby, Phogat, Sanjay, DiazGranados, Carlos A., Lee, Carter, Sinangil, Faruk, Michael, Nelson L., Robb, Merlin L., Kublin, James G., Gilbert, Peter B., McElrath, M. Juliana, Tomaras, Georgia D., Corey, Lawrence
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199879/
https://ncbi.nlm.nih.gov/pubmed/31534016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax1880
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