Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa

One of the most successful HIV vaccines to date, the RV144 vaccine tested in Thailand demonstratedcorrelates of protection including cross-clade V1V2 IgG breadth, Env-specific CD4+ T cell polyfunctionality, and antibody-dependent cellular cytotoxicity (ADCC) in vaccinees with low IgA binding. The HI...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Gray, Glenda E., Huang, Ying, Grunenberg, Nicole, Laher, Fatima, Roux, Surita, Andersen-Nissen, Erica, De Rosa, Stephen C., Flach, Britta, Randhawa, April K., Jensen, Ryan, Swann, Edith M., Bekker, Linda-Gail, Innes, Craig, Lazarus, Erica, Morris, Lynn, Mkhize, Nonhlanhla N., Ferrari, Guido, Montefiori, David C., Shen, Xiaoying, Sawant, Sheetal, Yates, Nicole, Hural, John, Isaacs, Abby, Phogat, Sanjay, DiazGranados, Carlos A., Lee, Carter, Sinangil, Faruk, Michael, Nelson L., Robb, Merlin L., Kublin, James G., Gilbert, Peter B., McElrath, M. Juliana, Tomaras, Georgia D., Corey, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199879/
https://ncbi.nlm.nih.gov/pubmed/31534016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax1880
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