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Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats

AIM: Butyrate is a major gut microbiota-derived metabolite. Reduced butyrate-producing bacteria has been reported in the spontaneously hypertensive rat (SHR), a model of hypertension characterized by dysfunctional autonomic nervous system and gut dysbiosis. Here, we demonstrate a potential mechanism...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Yang, Tao, Magee, Kacy L., Colon-Perez, Luis M., Larkin, Riley, Liao, Yan-Shin, Balazic, Eliza, Cowart, Jonathan R., Arocha, Rebeca, Redler, Ty, Febo, Marcelo, Vickroy, Thomas, Martyniuk, Christopher J., Reznikov, Leah R., Zubcevic, Jasenka
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199780/
https://ncbi.nlm.nih.gov/pubmed/30656835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13256
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