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Butyrate regulates inflammatory cytokine expression without affecting oxidative respiration in primary astrocytes from spontaneously hypertensive rats

Neurons and glia exhibit metabolic imbalances in hypertensive animal models, and loss of metabolic homeostasis can lead to neuroinflammation and oxidative stress. The objective of this study was to determine the effects of the microbial metabolite butyrate on mitochondrial bioenergetics and inflamma...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Yang, Tao, Rodriguez, Vermali, Malphurs, Wendi L., Schmidt, Jordan T., Ahmari, Niousha, Sumners, Colin, Martyniuk, Christopher J., Zubcevic, Jasenka
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056753/
https://ncbi.nlm.nih.gov/pubmed/30039527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13732
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